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Thiamine For Alzheimer's Disease


    Thiamine is an important vitamin, critical as a cofactor in many enzyme reactions. Alzheimer patients generally have low levels of thiamine in their blood [200-201].
    Thiamine has been given to alzheimer patients clinically and it has been shown to be mildly beneficial. One study gave patients 3 grams daily. Patient Mini Mental State Scores improved +1.35 ,compared with placebo scores of +0.54, a significant improvement [202]. Another study ,using doses of 3 to 8 grams of thiamine daily,also found improvement in mental function of patients [203]. One study did not find any improvement [204].