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Deprenyl For Alzheimer's Disease


   Deprenyl,also known as selegiline, is an inhibitor of the enzyme,monoamine oxidase B. Deprenyl can protect against radicals [50]and promotes nerve growth [51]. Deprenyl has been widely studied and used for the treatment of alzheimer's disease. Some studies show deprenyl has beneficial effects on alzheimer patients and an equal number of studies show no real benefit in alzheimer patients. At doses of 10 milligrams daily, deprenyl increases alertness [52],increases memory [53], and decreases depression and anxiety[54] in alzheimer patients. Many studies of deprenyl have been for less than 6 months. Two longer term studies, for 6 months and 15 months, have shown no changes in cognition in alzheimer patients [55-56].